ESCR Webinar 02 – Level Advanced
Date: Wednesday, March 13, 2019, at 18:00 CET
Title: “Modern techniques for Cardiac CT: Anatomy or function or both?“
Moderator: Dr. Maja Hrabak-Paar (Zagreb/HR)
"Assessment of coronary stenosis and FFR"
Dr. Carlo de Cecco, Atlanta/US
Prof. Rozemarijn Vliegenthart, Groningen/NL
Lecture 1 - details
The lecture will be focused on the actual state of the art in cardiac CT and the technical solutions available in clinical practice to obtain functional information on the coronary fractional flow reserve and myocardial perfusion.
• To describe the actual state of the art in cardiac CT
• To illustrate functional imaging techniques in cardiac CT
• To provide actual clinical results and application using CT myocardial Perfusion and CT Fractional Flow reserve
Patient with decreased fractional flow reserve in the left anterior descending artery (LAD) and matching myocardial hypoperfusionin the LAD territory.
About the speaker
Carlo N. De Cecco, MD, PhD is an Associate Professor of Radiology and Biomedical Informatics at Emory University in Atlanta. He is board certified from the American College of Radiology and the American College of Nuclear Medicine. His main scientific interest is cardiothoracic imaging and AI/ML applications. He has authored more than 180 articles in peer-reviewed scientific journals, eleven book chapters, and two books. He is on the editorial board of Radiology: Cardiothoracic Imaging and Investigative Radiology, associate editor for the Journal of Cardiovascular Computed Tomography, and he serves as the Artificial Intelligence/Machine Learning section editor for the European Journal for Radiology. He is a member of numerous scientific societies, and serves as Chair of the Cardiac Radiology Use Case Panel at the Data Science Institute (DSI) – American College of Radiology (ACR). He is a Fellow of the SCCT, NASCI, SCBTMR and ESGAR. Since 2014, he is a member of the Board of Experts of the Italian Ministry of Education, University and Research.
Lecture 2 - details
Many CTA-derived coronary stenoses do not cause ischemia. To determine the hemodynamic significance of a stenosis, the “downstream” blood supply is evaluated in myocardial perfusion imaging (MPI) techniques. Cardiac CT allows for anatomical and functional evaluation of coronary artery disease in one examination by adding CTMPI. There are two main CTMPI techniques to image myocardial ischemia, namely static and dynamic imaging. Dynamic CTMPI enables the quantification of myocardial blood flow, which may have particular advantages in f.e. multivessel disease. In recent years, numerous studies have shown the diagnostic accuracy of CT for assessment of myocardial ischemia, and the improvement of specificity for hemodynamically significant CAD compared to CTA alone. The lecture will include discussion of the current clinical status of CTMPI.
• To understand the potential value of CT perfusion
• To appreciate CT perfusion techniques
• To learn about the current clinical status of CT perfusion
CT perfusion transverse image, ischemia in LAD territory
About the speaker
Rozemarijn Vliegenthart studied medicine at the Erasmus University Rotterdam and the University of Groningen and obtained her MD degree (cum laude) in 2005. She obtained her PhD degree in 2003, and holds an MSc degree in Clinical Epidemiology. Vliegenthart works as a radiologist at the University Medical Center of Groningen. Research interests include validation and application of new techniques in cardiothoracic CT/MRI, centered on coronary artery disease, lung cancer and COPD. She has acquired a number of grants in cardiothoracic imaging as (co-)applicant. Vliegenthart is (co-)author on >180 scientific publications (H factor 37). She serves as Chairman of the cardiovascular section of the Dutch Radiology Society and as Secretary of the ESCR. Vliegenthart is Tenure track professor at the University of Groningen.